MEMBERS

Muriel Amblard

Research Director (CNRS)

MURIEL AMBLARD

Dr Muriel AMBLARD obtained her PhD in Organic Chemistry at the University of Montpellier under the supervision of Prof Jean Martinez in 1991. She joined the group of Dr Paul Anderson at Merck Sharp & Dohm in West point (Pennsylvania, USA) as a post-doctoral fellow. In 1996, she obtained a position at the Laboratory of Amino Acid Peptide and Protein in Montpellier as a CNRS researcher. She became a CNRS senior researcher and a team leader at the Institute of Biomolecules Max Mousseron in 2007. Her research interests are mainly at the interface of chemistry, biology and analysis

Jean Martinez

Professor Emeritus , Faculty of Pharmacy, University of Montpellier

Jean martinez

Jean Martinez received both his PhD in 1972 from the University of Montpellier 2 and his Dr Sciences Degree in 1976, under the supervision of Professor F. Winternitz. The same year, he joined Dr E. Bricas group at Orsay, University of Paris Sud, as a post-doctorate fellow and in 1977 the laboratory of Professor M. Bodanszky at Case Western Reserve University in Cleveland, USA, where he stayed till mid 1979. In 2007, he created the « Institut des Biomolécules Max Mousseron », which he has been the Director until December 2014. He is actually Head of the department of Amino Acids, Peptides and Proteins at IBMM.

Jean-Alain Fehrentz

Research Director (CNRS)

Jean-Alain Fehrentz

Jean-Alain Fehrentz was born in Nancy, France, in 1955. He received his Ph.D. degree in Chemistry from the University of Nancy in 1983 and joined the Centre CNRS-INSERM de Pharmacologie Endocrinologie of Montpellier in the research group of Professor B. Castro. From 1989 to 1992 he was appointed as researcher at Sanofi Research in Montpellier. Then he moved to the Faculty of Pharmacy of Montpellier, working under the direction of Professor J. Martinez. His research interests focus on peptide aldehydes, enzyme inhibitors, peptidomimetics, and heterocycle based receptor ligands. He published more than 150 scientific papers.

Gilles Subra

Professor, Faculty of Pharmacy, University of Montpellier

Gilles Subra

Gilles leads his researches in the Institute of Biomolécules Max Mousseron (IBMM) in the field of peptide science. His main research topics are at the interface of chemistry and biology and notably concern methodologies for solid phase and combinatorial chemistry, design of chemical tools to enhance detection and quantification by mass spectrometry in biological media. More recently, he is interested in the design of peptide-based materials and polymers. The main applications concern the conception of multi-ligand nanoparticles for cancer targeting, the functionalisation of silicone medical devices and dressings.

Baptiste Legrand

Research Engineer, University of Montpellier (UM)

Baptiste Legrand

Baptiste is a Research Engineer at the Institute of Biomolecules Max Mousseron (IBMM), University of Montpellier. He received his PhD in biology and life sciences from the University of Rennes 1 in 2009. Then, he moved for a two years post-doctoral fellowship at the Laboratory of Macromolecular Chemistry and Physics (LCPM, Nancy) working on the characterization of foldamers structures combining various techniques (NMR, CD and FTIR spectroscopies, and Molecular Dynamics) and then he joined the IBMM in 2012.

JEAN-FRANÇOIS HERNANDEZ

Research Director (CNRS)

Jean-François Hernandez

Jean-François Hernandez performed his PhD in the laboratory of Prof. Bernard P. Roques (Paris V University, 1987) under the supervision of Prof. Marie-Claude Fournié-Zaluski, where he developed pseudo-dipeptidic inhibitors of enkephalin-degrading enzymes as potential analgesics. Then, he went to the Salk Institute in San Diego as a post-doctoral fellow (1988-1990) under the supervision of Prof. Jean E. Rivier, where he learned solid phase peptide synthesis (Boc and Fmoc chemistries, GRF agonists, CRF antagonists, conotoxins, long peptides). 

Ludovic Maillard

Assistant professor, Faculty of Pharmacy, University of Montpellier

LUDOVIC maillaRd

Ludovic Maillard is Pharmacyst (Paris XI, 2002) and Chemical Engineer (ENSCP, Paris VI, 2002). After a Master Degree in organic chemistry (Paris VI, 2002), he did a PhD in bioorganic chemistry at the ICSN, in the group of Dr. B. Badet. Thereafter he joined the group of Prof. J. Robinson (OCI, Zurich, Switzerland) for a one-year post-doctoral fellow. He is actually Assistant Professor in medicinal chemistry.

One of his major research interests is to develop and characterized conformationaly predictable molecular architectures named foldamers, which are constructed from heterocyclic γ-amino acids

Séverine Denoyelle

Assistant Professor, Faculty of Pharmacy, University of Montpellier

severine denoyelle

After defending her Ph.D. in the field of bioorganic chemistry in 2005, Severine joined the Faculty of Pharmacy of Montpellier as a postdoctoral fellow. As part of the European project “Antimal”, her research work consisted in the development of new oral drugs for the treatment of Malaria. In 2007, Séverine started a two-year postdoctoral position at Harvard Medical School, Boston, MA, where she focused on the design and the synthesis of small molecules, namely diarylureas and oxindoles, for cancer therapy. In 2009, she became assistant professor in medicinal chemistry at the Faculty of Pharmacy of Montpellier where she joined the Institute of Biomolecules Max Mousseron (IBMM).

Luc Brunel

Chemical Engineer, CNRS – Synbio

luc brunel

Luc BRUNEL graduated from a DEA in heterocycle chemistry, polymers and catalysis obtained at the University of Montpellier in 1997. After several experiences in the private sector, since 2003 he has been working as a CNRS engineer in biomolecule development. He works on both the SynBio3 platform providing biomolecules of biological interest and pharmaceuticals, as responsible for syntheses and purifications in large quantities, but also within the research team of the laboratory to carry out certain precursor projects.

Laurent Gavara

Assistant professor, Faculty of Pharmacy, University of Montpellier

Laurent Gavara

Laurent Gavara completed his M. Sci. in 2005 in Montpellier and pursued his graduate studies under the supervision of Pr. Jean-Pierre Hénichart and Pr. Benoit Rigo at the University of Lille, where he received his Ph.D. in 2008. He conducted a first postdoctoral work for 2 years in Clermont-Ferrand in the Pascal Moreau group and then moved to a second postdoctoral position for 1 year in Fort Worth, US, with the Pr. Jean-Luc Montchamp. 

Nicolas Masurier

Professor, Faculty of Pharmacy, Montpellier University

Nicolas masurier

Nicolas Masurier was born in Yvetôt (France) in 1977. He first received his PharmD degree in 2003, before he obtained his PhD in 2006 from the University of Rouen (France) under the supervision of Prof. O. Lafont, working on the synthesis of β-cyclodextrin derivatives with hydrolytic activity against organophosphorous neurotoxics. Then, he moved to the University of Clermont-Ferrand (France) in the group of Pr. J.C. Teulade as an assistant-lecturer and worked on heterocyclic derivatives as tyrosine kinase inhibitors.

Pascal Verdier

Chemical engineer, University of Montpellier

Pascal verdié

Pascal Verdié, a chemical engineer from the Ecole Nationale Supérieure de Chimie of Montpellier, France, performed a PhD program in Chemistry and Biology Sciences for Health, Montpellier  University, which he graduated from in 2005. He worked on the development of selective ligands for the α-MSH MC1 receptor by the means of a huge program of peptide and combinatorial chemistry.

Alain Chavanieu

Professor, Faculty of Pharmacy, Montpellier University

ALAIN CHAVANIEU

Alain Chavanieu received his Ph.D. degree in Biochemistry from the University of Montpellier in 1992. After a post-doctoral period at the University of Birmingham (U.K.) in the group of Pr Barry Levine, he joined the Centre de Biochimie Structurale of Montpellier from 1985 to 2002 as post doctoral fellow then as associate professor. In 2011, he moved to the Institut des biomolecules Max Mousseron at the Faculty of Pharmacy of Montpellier, under the direction of Professor J. Martinez. His research interests focus on structure function of proteins and modulation of protein-protein interactions.

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Assistant Professor, Faculty of Pharmacy, University of Montpellier

YEN VO HUANG

Yen Vo-Hoang was born in Montpellier, France, in 1975. She received his Ph.D. degree in Chemistry from the University of René Descartes, Paris V in 2003. She moved to the Faculty of Pharmacy of Montpellier as assistant professor, working in the research group of Dr Thierry Durand from 2004 to 2013. Then she joined the research group of Dr Muriel Amblard. Her research interests focus on synthesis of pseudo-peptides to inhibit Arf1/Arno interaction.

Vincent Lisowski

Professor, Faculty of Pharmacy, University of Montpellier

VINCENT LISOWSKI

Vincent Lisowski was born in Aunay/Odon (France) in 1974. He first received his PharmD degree in 1998 before he obtained his PhD in 2002 from the University of Basse-Normandie, under the supervision of Professor Sylvain Rault in the field of new thiophene-based chemotherapeutic agents. After a postdoctoral position at the pharmaceutical faculty of Caen, where he developed medicinal projects in the field of cancer and Alzheimer’s disease, he joined the group of Professor Jean Martinez as an Assistant Professor at the University of Montpellier, in 2003.

Lubomir Vezenkov portrait

Assistant Professor, ENSCM

LUBOMIR Vezenkov

Lubomir Vezenkov performed a co-tutoring PhD between the universities of Montpellier and Naples, which he graduated from in 2011. Afterwards he did a two-years-long post-doctoral internship in the prof. Robert Young group in Simon Fraser University, Vancouver, working on the development of selective inhibitors of the autophagy.

Lubomir then moved back to Montpellier, and in 2016 he received an assistant professor position at ENSCM.

 

Sébastien Estran
Sébastien Estran

Chemical engineer, CNRS

sébastien Estaran

Sébastien ESTARAN graduated from a DESS in Structural Biology, obtained at the University of Montpellier in 2005. After a first experience as chemical analyst engineer in the pharmaceutical industry, he joined a team at the CBS, a structural laboratory in Montpellier, to work on a Fragment-Based Drug Design strategy to develop protein-protein interaction inhibitors. In 2017, he joined the IBMM as CNRS engineer specialized in molecular interactions studies.

Sébastien is currently working at the interface between chemistry and biology with skills in molecular modelling and protein biochemistry. Then using several biophysics technics, he characterizes protein-protein and protein-ligand interactions.

 

Pascal Dumy

Professor, ENSCM

Pascal Dumy

Pascal Dumy was appointed director of the National School of Chemistry, Montpellier (ENSCM) in February 2012. After a PhD carried out at the University of Montpellier 1 in 1993, he began his career at the University of Lausanne with Professor Manfred Mutter at the Institute of Organic Chemistry. In 1998 he joined the University of Grenoble 1 as a full professor in chemical biology. His research interest at IBMM focus on the design, synthesis and the validation of integrated functional systems and interfaces endowed with tailor-made properties for therapeutic and/or diagnostic applications or as model study against certain pathologies. He is co-author of over 200 publications.

 

Non permanent staff

Titouan Montheil
Titouan Montheil

After graduating from the ITECH (Institut Textile et Chimique de Lyon) – Lyon, major in polymer chemistry, Titouan Montheil is currently doing a PhD on hybrid hydrogels . He pursued this PhD in order to work in research of polymers and biopolymers applied to life sciences. His other areas of interest are sports and travel.

Julie Martin
Julie Martin

Julie graduated from the engineering school of Chemistry and Physics, specialized in Polymers, in Bordeaux – ENSCBP. She likes to travel, that is why she did two 5-months internships abroad.
She is doing a PhD on hybrid materials, based on a combination of peptides or pseudo peptides and a silica part.

Matthieu Simon
Matthieu Simon

Matthieu started working on peptides during an internship in India (IICT, Hyderabad). Then, he developed skills in biochemistry, molecular and structural biology during his PhD. (IGDR, Rennes). Matthieu is nowadays performing a post doctoral internship at IBMM, using foldamer chemistry developed in the laboratory, in order to design and synthesize innovative glycovectors for targeted drug delivery.

Manon Maurel
Manon Maurel

After graduating from Nice Sophia Antipolis University, Manon started working at IBMM for her internship. Then, she continued as an engineer working on peptides for the treatment of malaria. Recently, she  is working on peptides and biomaterials applied for cancer treatment.

Lisa-Maria Recnik
Lisa-Maria Recnik

Lisa graduated in Technical Chemistry from the University of Technology in Vienna in 2011. She spent one year as an Erasmus student at CPE Lyon. She then moved to the University of Bristol where she completed her PhD project on the development of novel inhibitors of kainate receptors under the supervision of Profs. Willis and Jane. In 2017, she joined the IBMM as a postdoctoral researcher working on the development of antibody-radiolabeled drug conjugates in collaboration with the IRCM.

Kevin Bourbiaux
Kevin Bourbiaux

Kévin Bourbiaux graduated from the University of Lille, major in “Chemistry and Life Sciences, Bio-organic Chemistry” in 2016. He has performed several internships in Medicinal Chemistry in the INSERM U1177 unit in Lille, working on small molecules synthesis. He is currently doing a PhD under a CIFRE agreement with SANOFI on foldamers and stapled peptides to inhibit protein-protein interaction in the field of cardiovascular diseases

Julie Aguesseau
Julie Aguesseau

Graduated with an Engineer’s Degree in Chemistry and Process Engineering from ESCPE Lyon in 2016, Julie Aguesseau is currently doing a PhD on the design of bio-inspired catalysts based on foldamer architectures. She has previously completed a 6-months internship in R&D at Sanofi, working on cyclopeptides characterization and synthesis. She has also been working for one year on the synthesis and purification of potentially bioactive in the Medicinal Chemistry Department of Origenis GmbH, Germany.

Jordi Rull
Jordi Rull

Jordi Rull obtained a PhD in 2010 at the University of Barcelona, working on the asymmetric synthesis of bioactive compounds. After an experience as co-founder of the start-up SINECTOR Jordi pursued his career in France at CEA, The University of Nantes and University of Strasbourg. In 2017 he joined the group of Dr. Muriel Amblard working on foldamers and stapled peptides medicinal chemistry in collaboration with Servier.

Christophe Cantelli
Christophe Cantelli

During his studies at the School of Pharmacy of Marseille, Christophe completed several internships in Medicinal Chemistry. In 2015, he moved to IBMM to do his master’s degree that he pursued with a PhD project. He is currently working on antibody-radiolabeled drug conjugates in cancer research in collaboration with the Institute of Cancer Research of Montpellier (IRCM) and acquired skills in radiobiology as well as synthetic chemistry.

Laurine Valot
Laurine Valot

Laurine Valot graduated from the Ecole Nationale Supérieure de Chimie de Montpellier, major in organic chemistry and biochemistry. Currently she is performing a PhD on 3D printing of hybrid hydrogel with mesenchymal stem cells to repair articulations. She pursue this PhD in order to work in research in chemistry and biology applied for health. Her main other areas of interest are art and board games.

Amandine Sandoval
Amandine Sandoval

Amandine work in e-dressing project under the supervision of Gilles Subra and Brice Sorli (IES). This PhD consists in the development of a smart wound dressing able to detect an enzymatic activity and to transmit information by passive RFID (radio frequency identification). The RFID device will be included into the dressing, in contact with the wound exudates. The antenna of the RFID device, will be grafted by a layer of hybrid material, sensitive to the degradation by enzymes related to the inflammation or infection of wounds.

 

Alexandre Messerschmitt
Alexandre Messerschmitt

Alexandre studied physics and chemistry at the University of Aix-Marseille. Then, he passed a Master degree in bimolecular chemistry at the University of Montpellier. Nowadays, he is in his third year of a PhD at IBMM, under the supervision of Dr. Muriel Amblard. He is synthetizing and characterizing new foldamers obtained from conversion of peptide sequences.

Alice Legru
Alice Legru

Alice LEGRU has just graduated from Master’s degree in Chemistry of Biomolecules from University of Montpellier. During her various internships, she has been working on the synthesis and purification of nucleoside derivatives, carbohydrates for the conception of anti-viral molecules and she developed a keen interest in medicinal chemistry.
Currently in first year of PhD, she works on the synthesis and physico-chemical characterization of enzyme inhibitors as anti-microbial drugs.

Julien Giribaldi
Julien Giribaldi
Julien was recently addopted by IBMM Peptide! After obtaining his master’s degree in biomolecule chemistry for health at the University of Montpellier. Julien began his PhD at the IBMM in 2016, supervised by Dr. Sébastien Dutertre and Pr. Christine Enjalbal, he works on the discovery, identification and synthesis of bioactive molecules derived from venoms.