1,3-Diazepine Derivatives: Strategies for Synthesis

Eur. J. Org. Chem., 2022, 21, e202100492, https://doi.org/10.1002/ejoc.202100492

Y. Malki, L.T. Maillard, N. Masurier


The present review describes the methodologies reported for the synthesis of 1,3-diazepine derivatives. This heterocyclic moiety forms the core structure of many compounds with potent biological activities. Synthetic strategies by ring closure or ring transformation are discussed.