MEMBERS

Muriel Amblard

Research Director (CNRS)

MURIEL AMBLARD

Dr Muriel AMBLARD obtained her PhD in Organic Chemistry at the University of Montpellier under the supervision of Prof Jean Martinez in 1991. She joined the group of Dr Paul Anderson at Merck Sharp & Dohm in West point (Pennsylvania, USA) as a post-doctoral fellow. In 1996, she obtained a position at the Laboratory of Amino Acid Peptide and Protein in Montpellier as a CNRS researcher. She became a CNRS senior researcher and a team leader at the Institute of Biomolecules Max Mousseron in 2007. Her research interests are mainly at the interface of chemistry, biology and analysis

Jean Martinez

Professor Emeritus , Faculty of Pharmacy, University of Montpellier

Jean martinez

Jean Martinez received both his PhD in 1972 from the University of Montpellier 2 and his Dr Sciences Degree in 1976, under the supervision of Professor F. Winternitz. The same year, he joined Dr E. Bricas group at Orsay, University of Paris Sud, as a post-doctorate fellow and in 1977 the laboratory of Professor M. Bodanszky at Case Western Reserve University in Cleveland, USA, where he stayed till mid 1979. In 2007, he created the « Institut des Biomolécules Max Mousseron », which he has been the Director until December 2014. He is actually Head of the department of Amino Acids, Peptides and Proteins at IBMM.

Jean-Alain Fehrentz

Research Director (CNRS)

Jean-Alain Fehrentz

Jean-Alain Fehrentz was born in Nancy, France, in 1955. He received his Ph.D. degree in Chemistry from the University of Nancy in 1983 and joined the Centre CNRS-INSERM de Pharmacologie Endocrinologie of Montpellier in the research group of Professor B. Castro. From 1989 to 1992 he was appointed as researcher at Sanofi Research in Montpellier. Then he moved to the Faculty of Pharmacy of Montpellier, working under the direction of Professor J. Martinez. His research interests focus on peptide aldehydes, enzyme inhibitors, peptidomimetics, and heterocycle based receptor ligands. He published more than 150 scientific papers.

Gilles Subra

Professor, Faculty of Pharmacy, University of Montpellier

Gilles Subra

Gilles leads his researches in the Institute of Biomolécules Max Mousseron (IBMM) in the field of peptide science. His main research topics are at the interface of chemistry and biology and notably concern methodologies for solid phase and combinatorial chemistry, design of chemical tools to enhance detection and quantification by mass spectrometry in biological media. More recently, he is interested in the design of peptide-based materials and polymers. The main applications concern the conception of multi-ligand nanoparticles for cancer targeting, the functionalisation of silicone medical devices and dressings.

Baptiste Legrand

Research Engineer, University of Montpellier (UM)

Baptiste Legrand

Baptiste is a Research Engineer at the Institute of Biomolecules Max Mousseron (IBMM), University of Montpellier. He received his PhD in biology and life sciences from the University of Rennes 1 in 2009. Then, he moved for a two years post-doctoral fellowship at the Laboratory of Macromolecular Chemistry and Physics (LCPM, Nancy) working on the characterization of foldamers structures combining various techniques (NMR, CD and FTIR spectroscopies, and Molecular Dynamics) and then he joined the IBMM in 2012.

JEAN-FRANÇOIS HERNANDEZ

Research Director (CNRS)

Jean-François Hernandez

Jean-François Hernandez performed his PhD in the laboratory of Prof. Bernard P. Roques (Paris V University, 1987) under the supervision of Prof. Marie-Claude Fournié-Zaluski, where he developed pseudo-dipeptidic inhibitors of enkephalin-degrading enzymes as potential analgesics. Then, he went to the Salk Institute in San Diego as a post-doctoral fellow (1988-1990) under the supervision of Prof. Jean E. Rivier, where he learned solid phase peptide synthesis (Boc and Fmoc chemistries, GRF agonists, CRF antagonists, conotoxins, long peptides). 

Ludovic Maillard

Assistant professor, Faculty of Pharmacy, University of Montpellier

LUDOVIC maillaRd

Ludovic Maillard is Pharmacyst (Paris XI, 2002) and Chemical Engineer (ENSCP, Paris VI, 2002). After a Master Degree in organic chemistry (Paris VI, 2002), he did a PhD in bioorganic chemistry at the ICSN, in the group of Dr. B. Badet. Thereafter he joined the group of Prof. J. Robinson (OCI, Zurich, Switzerland) for a one-year post-doctoral fellow. He is actually Assistant Professor in medicinal chemistry.

One of his major research interests is to develop and characterized conformationaly predictable molecular architectures named foldamers, which are constructed from heterocyclic γ-amino acids

Séverine Denoyelle

Assistant Professor, Faculty of Pharmacy, University of Montpellier

severine denoyelle

After defending her Ph.D. in the field of bioorganic chemistry in 2005, Severine joined the Faculty of Pharmacy of Montpellier as a postdoctoral fellow. As part of the European project “Antimal”, her research work consisted in the development of new oral drugs for the treatment of Malaria. In 2007, Séverine started a two-year postdoctoral position at Harvard Medical School, Boston, MA, where she focused on the design and the synthesis of small molecules, namely diarylureas and oxindoles, for cancer therapy. In 2009, she became assistant professor in medicinal chemistry at the Faculty of Pharmacy of Montpellier where she joined the Institute of Biomolecules Max Mousseron (IBMM).

Luc Brunel

Chemical Engineer, CNRS – Synbio

luc brunel

Luc BRUNEL graduated from a DEA in heterocycle chemistry, polymers and catalysis obtained at the University of Montpellier in 1997. After several experiences in the private sector, since 2003 he has been working as a CNRS engineer in biomolecule development. He works on both the SynBio3 platform providing biomolecules of biological interest and pharmaceuticals, as responsible for syntheses and purifications in large quantities, but also within the research team of the laboratory to carry out certain precursor projects.

Laurent Gavara

Assistant professor, Faculty of Pharmacy, University of Montpellier

Laurent Gavara

Laurent Gavara completed his M. Sci. in 2005 in Montpellier and pursued his graduate studies under the supervision of Pr. Jean-Pierre Hénichart and Pr. Benoit Rigo at the University of Lille, where he received his Ph.D. in 2008. He conducted a first postdoctoral work for 2 years in Clermont-Ferrand in the Pascal Moreau group and then moved to a second postdoctoral position for 1 year in Fort Worth, US, with the Pr. Jean-Luc Montchamp. 

Nicolas Masurier

Professor, Faculty of Pharmacy, Montpellier University

Nicolas masurier

Nicolas Masurier was born in Yvetôt (France) in 1977. He first received his PharmD degree in 2003, before he obtained his PhD in 2006 from the University of Rouen (France) under the supervision of Prof. O. Lafont, working on the synthesis of β-cyclodextrin derivatives with hydrolytic activity against organophosphorous neurotoxics. Then, he moved to the University of Clermont-Ferrand (France) in the group of Pr. J.C. Teulade as an assistant-lecturer and worked on heterocyclic derivatives as tyrosine kinase inhibitors.

Pascal Verdier

Chemical engineer, University of Montpellier

Pascal verdié

Pascal Verdié, a chemical engineer from the Ecole Nationale Supérieure de Chimie of Montpellier, France, performed a PhD program in Chemistry and Biology Sciences for Health, Montpellier  University, which he graduated from in 2005. He worked on the development of selective ligands for the α-MSH MC1 receptor by the means of a huge program of peptide and combinatorial chemistry.

Alain Chavanieu

Professor, Faculty of Pharmacy, Montpellier University

ALAIN CHAVANIEU

Alain Chavanieu received his Ph.D. degree in Biochemistry from the University of Montpellier in 1992. After a post-doctoral period at the University of Birmingham (U.K.) in the group of Pr Barry Levine, he joined the Centre de Biochimie Structurale of Montpellier from 1985 to 2002 as post doctoral fellow then as associate professor. In 2011, he moved to the Institut des biomolecules Max Mousseron at the Faculty of Pharmacy of Montpellier, under the direction of Professor J. Martinez. His research interests focus on structure function of proteins and modulation of protein-protein interactions.

XX

Assistant Professor, Faculty of Pharmacy, University of Montpellier

YEN VO HUANG

Yen Vo-Hoang was born in Montpellier, France, in 1975. She received his Ph.D. degree in Chemistry from the University of René Descartes, Paris V in 2003. She moved to the Faculty of Pharmacy of Montpellier as assistant professor, working in the research group of Dr Thierry Durand from 2004 to 2013. Then she joined the research group of Dr Muriel Amblard. Her research interests focus on synthesis of pseudo-peptides to inhibit Arf1/Arno interaction.

Vincent Lisowski

Professor, Faculty of Pharmacy, University of Montpellier

VINCENT LISOWSKI

Vincent Lisowski was born in Aunay/Odon (France) in 1974. He first received his PharmD degree in 1998 before he obtained his PhD in 2002 from the University of Basse-Normandie, under the supervision of Professor Sylvain Rault in the field of new thiophene-based chemotherapeutic agents. After a postdoctoral position at the pharmaceutical faculty of Caen, where he developed medicinal projects in the field of cancer and Alzheimer’s disease, he joined the group of Professor Jean Martinez as an Assistant Professor at the University of Montpellier, in 2003.

Lubomir Vezenkov portrait

Assistant Professor, ENSCM

LUBOMIR Vezenkov

Lubomir Vezenkov performed a co-tutoring PhD between the universities of Montpellier and Naples, which he graduated from in 2011. Afterwards he did a two-years-long post-doctoral internship in the prof. Robert Young group in Simon Fraser University, Vancouver, working on the development of selective inhibitors of the autophagy.

Lubomir then moved back to Montpellier, and in 2016 he received an assistant professor position at ENSCM.

Sébastien Estran

Chemical engineer, CNRS

sébastien Estaran

Sébastien ESTARAN graduated from a DESS in Structural Biology, obtained at the University of Montpellier in 2005. After a first experience as chemical analyst engineer in the pharmaceutical industry, he joined a team at the CBS, a structural laboratory in Montpellier, to work on a Fragment-Based Drug Design strategy to develop protein-protein interaction inhibitors. In 2017, he joined the IBMM as CNRS engineer specialized in molecular interactions studies.

Sébastien is currently working at the interface between chemistry and biology with skills in molecular modelling and protein biochemistry. Then using several biophysics technics, he characterizes protein-protein and protein-ligand interactions.

Pascal Dumy

Professor, ENSCM

Pascal Dumy

Pascal Dumy was appointed director of the National School of Chemistry, Montpellier (ENSCM) in February 2012. After a PhD carried out at the University of Montpellier 1 in 1993, he began his career at the University of Lausanne with Professor Manfred Mutter at the Institute of Organic Chemistry. In 1998 he joined the University of Grenoble 1 as a full professor in chemical biology. His research interest at IBMM focus on the design, synthesis and the validation of integrated functional systems and interfaces endowed with tailor-made properties for therapeutic and/or diagnostic applications or as model study against certain pathologies. He is co-author of over 200 publications.

Sonia Cantel

Assistant Professor-HDR, Faculty of Sciences, Faculty of Pharmacy, University of Montpellier

Sonia Cantel

Sonia Cantel obtained her PhD in 2004 in Chemistry of Biomolecules from the University of Montpellier, under the supervision of Dr. J-A Fehrentz, in the field of pseudo-peptide and solid phase organic synthesis. Then, she joined the group of Pr. M. Chorev for the following two years as a Postdoctoral Fellow in the Laboratory for Translational Research (Harvard Medical School, Boston, USA). She actively participated to biomedicinal projects where chemistry plays a critical role but also required the input of other scientific disciplines. In this interdisciplinary research environment, she developed extensive skills in analytical techniques applied to protein engineering.

Her accomplishments included development of new methodologies for synthesis of glycated antigenic peptides and in situ templated assembly of fragments to generate potent inhibitors of protein-protein interaction.

Anthony Martin 2

Researcher – CNRS, HDR

anthony martin

Anthony R. Martin received his PhD from the University of Montpellier in 2011 under the supervision of Prof. Michael Smietana and Dr. Jean-Jacques Vasseur, working on the synthesis and self-assembly of borono(oligo)nucleotides. He then joined Prof. Steven Nolan’s group (Saint-Andrews University) as a postdoctoral researcher to work on late transition metal coordination and their applications in homogeneous catalysis. In 2013, he moved to the Institute of Chemistry of Nice in Dr. Benhida’s group where he was appointed Chargé de Recherche — CNRS in 2014. There, he mainly focused his research on medicinal chemistry programs devoted to the tackling of chemoresistance in cancers. Additionally, he developed chemical biology tools to monitor and probe enzymatic activities in live cells. In 2020, Anthony moved to the Institut des Biomolécules Max Mousseron (Montpellier), in Dr Amblard’s group, where his current researches encompass various aspects of peptide chemistry and the exploration of new modalities for the targeted degradation of proteins.

Non permanent staff

Raquel Gutiérrez-Climente
Raquel Gutiérrez-Climente

Raquel received her PhD in 2015 at the department of Analytical Chemistry, University of Basque Country (Spain). After a first 2 years Postdoc fellow in the department of Enzyme and Cell Engineering at the University of Technology of Compiègne (France), she is since 2019 a Postdoc at the University of Montpellier in the Institute of Biomolecules Max Mousseron (IBMM) and the Institute Charles Gerhardt (ICG). Her present research interest include affinity technology, hybrid materials and molecularly imprinted polymers for protein recognition in biomedical applications.

Margaux Clavié
Margaux Clavié

Graduated with a Master’s degree in Chemistry of Biomolecules at the University of Montpellier, Margaux has developed a keen interest in interface between chemistry and biology during her studies and internships. In particular, she was able to work on the synthesis and characterization of polycationic γ-peptide foldamers for antimicrobial applications. Margaux is currently doing a PhD on biomimetic molecular imprinting for protein recognition system.

Mathilde Guérin
Mathilde Guérin

After graduated from ECPM (European Engineering School of Chemical, Polymer and Materials), specialized in molecular chemistry, in Strasbourg and she obtained her Master’s degree of molecular and supramolecular chemistry at the University of Strasbourg. She performed several interships in Medical Chemistry as well as in private and academic research laboratories. In particular, she was able to work about Chikungunya virus during 7 months in Vienna (Austria). Now, Mathilde Guérin is currently doing a PhD on hybrid hydroxyapatite particles for the wound healing treatment.

Manon Maurel
Manon Maurel

After graduating from a Master degree in Chemistry at Nice Sophia Antipolis University, Manon started working on enzyme inhibitors at IBMM for her internship. Then, she continued as a chemical engineer working on the development of malaria treatment using solid phase peptide synthesis and organic chemistry. Afterwards, she worked on peptides and nanoparticles applied for cancer treatment, leading to the publication of various articles. Recently, she is working on the synthesis of peptides and peptide analogues for the treatment of glioblastomas.

Amandine Sandoval
Amandine Sandoval

Amandine work in e-dressing project under the supervision of Gilles Subra and Brice Sorli (IES). This PhD consists in the development of a smart wound dressing able to detect an enzymatic activity and to transmit information by passive RFID (radio frequency identification). The RFID device will be included into the dressing, in contact with the wound exudates. The antenna of the RFID device, will be grafted by a layer of hybrid material, sensitive to the degradation by enzymes related to the inflammation or infection of wounds.

Alice Legru
Alice Legru

Alice graduated from Master’s degree in Chemistry of Biomolecules from University of Montpellier. She just obtained a PhD, working on the synthesis and physico-chemical characterization of enzyme inhibitors as anti-microbial drugs under the supervision of Jean-François Hernandez and Laurent Gavara. She continued as a postdoctoral researcher working on the development of metallo-β-lactamases inhibitors to fight the bacterial resistance to β-lactam antibiotics.

Julie Martin
Julie Martin

Julie graduated from the engineering school of Chemistry and Physics, specialized in Polymers, in Bordeaux – ENSCBP. She likes to travel, that is why she did two 5-months internships abroad.
She is doing a PhD on hybrid materials, based on a combination of peptides or pseudo peptides and a silica part.

Matthieu Simon
Matthieu Simon

Matthieu started working on peptides during an internship in India (IICT, Hyderabad). Then, he developed skills in biochemistry, molecular and structural biology during his PhD. (IGDR, Rennes). Matthieu is nowadays performing a post doctoral internship at IBMM, using foldamer chemistry developed in the laboratory, in order to design and synthesize innovative glycovectors for targeted drug delivery.

Alexandre Desfoux
Alexandre Desfoux

Alexandre is graduated in Biomolecules research and innovation from University of Montpellier. He just started his CIFRE PhD project with ProGeLife on the development of a drug against the Progeria disease and developing his skills in peptide synthesis, analysis and formulation.

Prisca Lagardère
Prisca Lagardère

Prisca graduated in Organic Chemistry and Life Sciences from the University of Bordeaux in 2018. During her several internships, she has been working on small molecules synthesis and she developed a keen interest on medicinal chemistry. Currently in third year of PhD, she is working on the synthesis and the characterization of new antimalarial thienopyrimidinones.

Yohan Malki
Yohan Malki

Yohan Malki is graduated from the Ecole Nationale Supérieure de Chimie of Montpellier, major in organic chemistry in 2018. He has performed several internships in medicinal chemistry in industry and overseas (Sherbrooke, Canada). Currently, Yohan is doing his PhD on the synthesis of 1,3-diazepine derivatives for the treatment of melanoma with Prof. Nicolas Masurier at the Institute of Biomolecules Max Mousseron in Montpellier, France.

Pauline Adler
Pauline Adler

Pauline Adler obtained her PhD in Organic Chemistry in 2016 at the University of Paris-Saclay, under the supervision of Dr. N. Rabasso. She joined the group of Pr. N. Maulide at the University of Vienna in Austria as a post-doctoral fellow for two years (2017 – 2018). After this, she became an Assistant Professor at the University of Montpellier and worked in the group of Dr. C. Grison for two years (2018 – 2020). In 2020, she joined IBMM as a post-doctoral researcher, working with Dr. J.-F. Hernandez on pseudopeptides as potential treatments of malaria.

Anna Puszko
Anna Puszko

Anna received her PhD in 2018 at the Faculty of Chemistry, University of Warsaw (Poland). She continued her research as Research Assistant and later Assistant Professor. In 2020 she obtained MSCA fellowship and started a postdoc at the University of Montpellier in the Institute of Biomolecules Max Mousseron (IBMM), under the supervision of Dr. Jean-François Hernandez. Her current research is focused on pseudopeptides as a potential treatment in malaria. The interdisciplinary project is carried out in cooperation with the Pasteur Institute in Paris.

Miyanou Rosales-Hurtado
Miyanou Rosales-Hurtado

Miyanou holds a masterʼs degree in Molecular and Macromolecular Chemistry at the University of Bordeaux. In 2019, she received her Ph.D. in medicinal chemistry at the University of Nîmes on the development of potential inhibitors of histidine kinase under the supervision of Prof. Meffre and Dr. Benfodda. She joined the IBMM as a postdoctoral researcher in 2020 where her current interest concerns how to overcome bacteria resistance mediated by β-lactamase.

Mylene Sejalon-Cipolla
Mylene Sejalon-Cipolla

Mylene graduated from the National Chemistry School of Montpellier, majoring in Biochemistry and Organic chemistry. After one year spent at the Oxford University where she worked on the synthesis and analysis of glyco-derivative antivirals for HIV and Hepatitis treatment, she started her PhD at IBMM under the supervision of Dr. Sonia CANTEL and Pr. Gilles Subra. Begining her third year, she is currently working on the synthesis and evaluation of designed activity based probes for inflammatory diseases early diagnosis for MALDI mass spectrometry and MALDI imaging.

Anthony Feral
Anthony Feral

Anthony graduated from master’s degree in Chemistry of Biomolecules: Research and Innovation at Montpellier University (France). During his master’s internships, he worked on the synthesis and the rational design of pseudopeptides; then he worked on the elaboration and the synthesis of small-molecule-based PROTAC compounds. These two internships were performed at the IBMM Peptide Team. Nowadays, Anthony is working as a study engineer with Dr. Lubomir Vezenkov and MT-Act, a start-up, on the conception of therapeutical pseudopeptides and PROTACs.

Cécile Echalier
Cécile Echalier

Cécile Echalier is currently a contract assistant professor at the University of Montpellier, with expertise in biomaterials and chemical biology. She studied organic and biomolecular chemistry at the University of Montpellier. There, she dedicated her PhD to the synthesis and evaluation of biomimetic materials for tissue engineering applications. After her PhD, she joined the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. In collaboration with GlaxoSmithKline, she developed chemical tools to elucidate the mode of action of drug candidates. In 2019, she joined the Stevens group at Imperial College London, UK. She was awarded a Scientia fellowship to develop an islets-on-chip platform with integrated biosensors in collaboration with the University of Oslo, Norway. She recently returned to Montpellier to resume her research on biomimetic hybrid materials for regenerative applications.

Past Members

Lisa-Maria Recnik
Lisa-Maria Recnik

Lisa graduated in Technical Chemistry from the University of Technology in Vienna in 2011. She spent one year as an Erasmus student at CPE Lyon. She then moved to the University of Bristol where she completed her PhD project on the development of novel inhibitors of kainate receptors under the supervision of Profs. Willis and Jane. In 2017, she joined the IBMM as a postdoctoral researcher working on the development of antibody-radiolabeled drug conjugates in collaboration with the IRCM.

Kevin Bourbiaux
Kevin Bourbiaux

Kévin Bourbiaux graduated from the University of Lille, major in “Chemistry and Life Sciences, Bio-organic Chemistry” in 2016. He has performed several internships in Medicinal Chemistry in the INSERM U1177 unit in Lille, working on small molecules synthesis. He is currently doing a PhD under a CIFRE agreement with SANOFI on foldamers and stapled peptides to inhibit protein-protein interaction in the field of cardiovascular diseases.

Julie Aguesseau
Julie Aguesseau

Graduated with an Engineer’s Degree in Chemistry and Process Engineering from ESCPE Lyon in 2016, Julie Aguesseau is currently doing a PhD on the design of bio-inspired catalysts based on foldamer architectures. She has previously completed a 6-months internship in R&D at Sanofi, working on cyclopeptides characterization and synthesis. She has also been working for one year on the synthesis and purification of potentially bioactive in the Medicinal Chemistry Department of Origenis GmbH, Germany.

Jordi Rull
Jordi Rull

Jordi Rull obtained a PhD in 2010 at the University of Barcelona, working on the asymmetric synthesis of bioactive compounds. After an experience as co-founder of the start-up SINECTOR Jordi pursued his career in France at CEA, The University of Nantes and University of Strasbourg. In 2017 he joined the group of Dr. Muriel Amblard working on foldamers and stapled peptides medicinal chemistry in collaboration with Servier.

Christophe Cantelli
Christophe Cantelli

During his studies at the School of Pharmacy of Marseille, Christophe completed several internships in Medicinal Chemistry. In 2015, he moved to IBMM to do his master’s degree that he pursued with a PhD project. He is currently working on antibody-radiolabeled drug conjugates in cancer research in collaboration with the Institute of Cancer Research of Montpellier (IRCM) and acquired skills in radiobiology as well as synthetic chemistry.

Laurine Valot
Laurine Valot

Laurine Valot graduated from the Ecole Nationale Supérieure de Chimie de Montpellier, major in organic chemistry and biochemistry. She performed her PhD on 3D bio-printing of hybrid hydrogel with mesenchymal stem cells to repair articulations, in the IBMM peptide team. She is now pursuing new research in the development of hybrid peptide-based foams and multifunctional hybrid peptide-based hydrogels for cell culture with a short Post-doc position in the team.

Julien Giribaldi
Julien Giribaldi

Julien was recently addopted by IBMM Peptide! After obtaining his master’s degree in biomolecule chemistry for health at the University of Montpellier. Julien began his PhD at the IBMM in 2016, supervised by Dr. Sébastien Dutertre and Pr. Christine Enjalbal, he works on the discovery, identification and synthesis of bioactive molecules derived from venoms.

Alexandre Messerschmitt
Alexandre Messerschmitt

Alexandre studied physics and chemistry at the University of Aix-Marseille. Then, he passed a Master degree in bimolecular chemistry at the University of Montpellier. Nowadays, he is in his third year of a PhD at IBMM, under the supervision of Dr. Muriel Amblard. He is synthetizing and characterizing new foldamers obtained from conversion of peptide sequences.

Titouan Montheil
Titouan Montheil

After graduating from the ITECH (Institut Textile et Chimique de Lyon) – Lyon, major in polymer chemistry, Titouan Montheil is currently doing a PhD on hybrid hydrogels . He pursued this PhD in order to work in research of polymers and biopolymers applied to life sciences. His other areas of interest are sports and travel.