Professor, Faculty of Pharmacy of Montpellier
Gilles leads his researches in the Institute of Biomolécules Max Mousseron (IBMM) in the field of peptide science. His main research topics are at the interface of chemistry and biology and notably concern methodologies for solid phase and combinatorial chemistry, design of chemical tools to enhance detection and quantification by mass spectrometry in biological media. More recently, he is interested in the design of peptide-based materials and polymers. The main applications concern the conception of multi-ligand nanoparticles for cancer targeting, the functionalisation of silicone medical devices and dressings. His most recent research is related to the design of biomimetic peptide based hydrogel used for 3D biofabrication and cell-based therapies.
Gilles Subra founded the solid phase and automated synthesis platform (SynBio3) of the IBMM whose mission is to develop solid supported reagents, linkers and methodologies for the synthesis of biomolecules.
+33 411 75 96 06
5 major publications :
Ciccione, J., Jia, T., Coll, J.-L., Parra, K., Amblard, M., Jebors, S., Martinez, J., Mehdi, A., and Subra, G. (2016). Unambiguous and Controlled One-Pot Synthesis of Multifunctional Silica Nanoparticles. Chem. Mater. 28, 885–889.
Echalier, C., Pinese, C., Garric, X., Van Den Berghe, H., Jumas Bilak, E., Martinez, J., Mehdi, A., and Subra, G. (2016). Easy Synthesis of Tunable Hybrid Bioactive Hydrogels. Chem. Mater. 28, 1261–1265.
Jebors, S., Ciccione, J., Al-Halifa, S., Nottelet, B., Enjalbal, C., M’Kadmi, C., Amblard, M., Mehdi, A., Martinez, J., and Subra, G. (2015). A New Way to Silicone-Based Peptide Polymers. Angew. Chem. Int. Ed. 54, 3778–3782.
Paramelle, D., Subra, G., Vezenkov, L.L., Maynadier, M., André, C., Enjalbal, C., Calmès, M., Garcia, M., Martinez, J., and Amblard, M. (2010). A Straightforward Approach for Cellular-Uptake Quantification. Angewandte Chemie International Edition 49, 8240–8243.
Paramelle, D., Enjalbal, C., Amblard, M., Forest, E., Heymann, M., Cantel, S., Geourjon, C., Martinez, J., and Subra, G. (2011). Solid-Phase Cross-Linking (SPCL): A new tool for protein structure studies. PROTEOMICS 11, 1277–1286.