Professor, Faculty of Pharmacy, University OF MONTPELLIER
Vincent Lisowski was born in Aunay/Odon (France) in 1974. He first received his PharmD degree in 1998 before he obtained his PhD in 2002 from the University of Basse-Normandie, under the supervision of Professor Sylvain Rault in the field of new thiophene-based chemotherapeutic agents. After a postdoctoral position at the pharmaceutical faculty of Caen, where he developed medicinal projects in the field of cancer and Alzheimer’s disease, he joined the group of Professor Jean Martinez as an Assistant Professor at the University of Montpellier, in 2003. He was appointed Professor of Medicinal Chemistry at the School of Pharmacy in 2012. His research interests are peptide & heterocyclic chemistry applied to projects in the fields of medicinal chemistry (enzyme inhibitors, drug delivery) and chemical biology (antibody drug conjugate)
5 major publications :
Masurier, Arama, D.P.; N; El Amri, C.; Lisowski, V. Physiological and synthetic inhibitors of tissue kallikreins: an overview. Med. Res. Rev., 2017, accepted.
Mathieu, L.; Bonnel, C.; Masurier, N.; Maillard, L. T.; Martinez, J.; Lisowski, V. Cross-Claisen Condensation of N-Fmoc-Amino Acids – A Short Route to Heterocyclic gamma-Amino Acids. European Journal of Organic Chemistry 2015, 2262-2270.
Denoyelle, S.; Tambutet, G.; Masurier, N.; Maillard, L. T.; Martinez, J.; Lisowski, V. Synthesis of Thieno[3,2-e][1,4]diazepin-2-ones: Application of an Uncatalysed Pictet-Spengler Reaction. European Journal of Organic Chemistry 2015, 7146-7153.
Legrand, B.; Mathieu, L.; Lebrun, A.; Andriamanarivo, S.; Lisowski, V.; Masurier, N.; Zirah, S.; Kang, Y. K.; Martinez, J.; Maillard, L. T. Thiazole-Based gamma-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation. Chemistry-a European Journal 2014, 20, 6713-6720.
Malcor, J.-D.; Payrot, N.; David, M.; Faucon, A.; Abouzid, K.; Jacquot, G.; Floquet, N.; Debarbieux, F.; Rougon, G.; Martinez, J.; Khrestchatisky, M.; Vlieghe, P.; Lisowski, V. Chemical Optimization of New Ligands of the Low-Density Lipoprotein Receptor as Potential Vectors for Central Nervous System Targeting. Journal of Medicinal Chemistry 2012, 55, 2227-2241.