Professor, Faculty of Pharmacy, Montpellier University
Nicolas Masurier was born in Yvetôt (France) in 1977. He first received his PharmD degree in 2003, before he obtained his PhD in 2006 from the University of Rouen (France) under the supervision of Prof. O. Lafont, working on the synthesis of β-cyclodextrin derivatives with hydrolytic activity against organophosphorous neurotoxics. Then, he moved to the University of Clermont-Ferrand (France) in the group of Pr. J.C. Teulade as an assistant-lecturer and worked on heterocyclic derivatives as tyrosine kinase inhibitors. He is currently professor in medicinal chemistry at the Faculty of Pharmacy of Montpellier. He worked at the Institut des Biomolécules Max Mousseron (IBMM), where his current research interests focus on the design, the preparation of new anticancer agents and kallikrein inhibitors.
5 major publications :
V. Bellet, L. Lichon, D. P. Arama, A. Gallud, V. Lisowski, L. T. Maillard, M. Garcia, J. Martinez, N. Masurier, Imidazopyridine-fused [1,3]-diazepinones Part 2: Structure-Activity Relationships and antiproliferative activity against melanoma cells, Eur. J. Med. Chem., 2017, 125, 1225-34
D. P. Arama, F. Soualmia, V. Lisowski, J.-F. Longevial, E Bosc, L. T. Maillard, J. Martinez, N. Masurier, C. El Amri, Pyrido-imidazodiazepinones as a new class of reversible inhibitors of human kallikrein 7, Eur. J. Med. Chem., 2015, 93, 202-213
A. Gallud, O. Vaillant, L.T. Maillard, D.P. Arama, J. Dubois, V. Lisowski, M. Garcia, J. Martinez, N. Masurier, Imidazopyridine-fused [1,3]-diazepinones: Synthesis and antiproliferative activity, Eur. J. Med. Chem., 2014, 75, 382-390
N. Masurier, R. Aruta, V. Gaumet, S. Denoyelle, E. Moreau, V. Lisowski, J. Martinez, L. T. Maillard, Selective C-Acylation of 2-Aminoimidazo[1,2-a]pyridine: Application to the Synthesis of Imidazopyridine-Fused [1,3]Diazepinones, J. Org. Chem., 2012, 77 (7), 3679-3685
N. Masurier, P. Zajdel, P. Verdié, M. Pawlowski, M. Amblard, J. Martinez, G. Subra, A new highly versatile handle for chemistry on solid support: the Pipecolic linker – Part 2, Chem. Eur. J., 2012, 18 (37), 11536-11540